H-Cube Midi™

The H-Cube Midi™ represents the first step in the ThalesNano, Inc.’s development towards process scale-up flow hydrogenation. Utilizing current H-Cube^® technology, the H-Cube Midi™ seeks to increase the capacity of the present H-Cube^® to 500 g per day without compromising efficiency and safety. The H-Cube Midi™ will allow users of the H-Cube^® to scale up reactions and achieve the same result.

The H-Cube Midi™ system works through the hydrogenation of a continuous flow of substrate. The substrate is flowed through the system using an automatically controlled piston-pump at flow-rates up to 25 mL/min. Once entering the H-Cube Midi™ reaction line, the flow of substrate is mixed with a continuous flow of hydrogen.

The hydrogen is created by the electrolysis of water within an electrolytic cell. The electrolytic cell is based on the original H-Cube^® cell, but has been modified for a larger output of hydrogen. The hydrogen gas and a solution of the reactant are mixed, pre-heated and transferred to a catalyst cartridge (MidiCart™) that is preloaded with the required heterogeneous catalysts.

Advantages

Safer

• No gas cylinder or other external hydrogen source
• Can be used in standard laboratories
• No catalyst filtration or direct catalyst handling
• Easy catalyst exchange

Efficient

• Analyze reaction results within minutes
• Higher reaction rates with increased phase mixing
• Easy to use, touch screen controlled
• Experiments run on the standard H-Cube® can be replicated in the H-Cube Midi™ easily - about one day is needed to convert the process.

Convenient

• Compact size can be used in a standard laboratory fume hood
• No special training or skill is required to operate